Resistant dextrin may boost satiety, help blood sugar levels in healthy adults: RCT

By Stephen Daniells

- Last updated on GMT

© JONGHO SHIN / Getty Images
© JONGHO SHIN / Getty Images

Related tags Resistant dextrin Roquette satiety Weight management

Daily supplementation with Roquette’s Nutriose resistant dextrin may boost the feeling of fullness and blunted blood sugar spikes in healthy adults living in the UK, says a new study.

The data, which is published in the European Journal of Nutrition​, also showed that 14 grams per day of the resistant dextrose also led to significant reductions in blood pressure after 28 days for normal weight people.

The new study was welcomed by Laetitia Guerin-Deremaux, Head of Nutrition and Health, R&D, Roquette, who told NutraIngredients-USA: “This new clinical demonstration of a long-term impact of Nutriose on satiety-related parameters, blood glucose management, and blood pressure may be explained by the gut microbiota modulation already described for Nutriose soluble fiber.

“Following the definition of prebiotic proposed by ISAPP*, we can consider that Nutriose soluble fiber is a prebiotic. Why? We already know that Nutriose is a substrate that is selectively utilized by host microorganisms, and, here with this new study, we continue to develop our bundle of evidence on the demonstrated health benefits of Nutriose​.

Weight management potential

Guerin-Deremaux added that weight control is a primary motivator for two out of every three consumers who say they have changed their diet in the past year, according to Innova Market Insights**.

“Feeling hungry is the biggest obstacle to sticking with healthy eating habits, creating an opportunity for manufacturers to incorporate and highlight satiating ingredients into new products,” ​she noted. “Among the consumers following a diet, high protein and high fiber are the most followed types. When deciding what to purchase, low sugar and low fat have the most significant influence. Also, most consumers say they are actively avoiding or reducing their sugar intake.”

Roquette’s Nutriose is a range of soluble fibers coming from non-GMO wheat or corn. The new study builds on earlier findings supporting the ingredient’s weight management potential in a study with overweight Chinese men (Guérin-Deremaux et al., 2011, Nutrition Research​, Vol 31, pp. 665–672).

Study details

The new study included 20 normal weight and 16 overweight adults randomly assigned to receive either 14 grams per day of Nutriose or placebo (maltodextrin) for 28 days. This was followed by 28 days of no intervention (the ‘washout’ period) before the participants were crossed over to the other intervention for a further 28 days.

Results showed that, compared to the control, chronic supplementation with Nutriose was associated with higher satiety scores after 14 and 28 days. However, no significant changes were recorded for energy intakes, and body measures such as body weight, body fat, waist circumference and hip circumference in either group.

The researchers also note that the resistant dextrin (RD) was associated with a reduction in the glycemic response to a mid-morning intervention drink.

“Intervention studies of a greater duration are needed to determine whether RD consumption can help regulate body weight and influence metabolic health,”​ wrote the researchers.

Improvements in systolic blood pressure after 14 days was also recorded by the researchers, but these were limited to the people with normal weight, and not the overweight participants.

“From a mechanistic perspective studies of the differential impact of RD on the microbiota of normal and overweight individuals might help to explain our findings,”​ they wrote, before concluding, “The observed potential anti-hypertensive properties of RD are of interest but require further investigation.”

Source: European Journal of Nutrition​ 
Published online ahead of print, doi: 10.1007/s00394-021-02618-9
“Impact of dietary supplementation with resistant dextrin (NUTRIOSE) on satiety, glycaemia, and related endpoints, in healthy adults”
Authors: M.R. Hobden, et al.

* Gibson, et al. 2017, “Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics”, Nature Reviews Gastroenterology & Hepatology​, Vol 14, pp 491–502, doi: 10.1038/nrgastro.2017.75

** Innova Market Insights 2020 - Diet and Weight Loss Trends Global

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